Opportunity Information: Apply for RFA CA 20 050
The New Cohorts for Environmental Exposures and Cancer Risk (CEECR) Coordinating Center funding opportunity (RFA-CA-20-050) is a National Institutes of Health cooperative agreement (U24, clinical trial not allowed) led by the National Cancer Institute (NCI) in partnership with the National Institute of Environmental Health Sciences (NIEHS). Its purpose is to fund a single Coordinating Center that will serve as the organizing and operational hub for the broader CEECR program, which is building and supporting new prospective cohort studies focused on how environmental exposures contribute to cancer risk. The CEECR program is designed to close key evidence gaps in cancer etiology by improving the quality, comparability, and usability of data on environmental exposures, while also accounting for genetic, lifestyle, and behavioral factors that can modify cancer risk across diverse populations. This Coordinating Center is intended to work closely with the new cohort awards funded under a companion announcement (RFA-CA-20-049, UG3/UH3 phased awards), helping ensure that multiple independently run cohorts can still generate harmonized, high-value data and biospecimens that are useful for cross-cohort analyses.
A central theme of this opportunity is coordination rather than conducting primary research or clinical trials. The Coordinating Center is expected to provide administrative and logistical support for the CEECR program as a whole, enabling consistent practices and smooth collaboration among participating cohort studies. Core responsibilities include developing and disseminating standard operating procedures and best practices for collecting core common data elements and biological samples, which is crucial for making results comparable across cohorts and for enabling pooled analyses later. The Coordinating Center is also expected to facilitate communication across cohorts, which typically means setting up regular touchpoints, shared workflows, and collaborative problem-solving structures so that cohorts align on data standards, biospecimen handling, and exposure measurement approaches. In addition, it is responsible for meeting support, which can include planning and running program meetings, coordinating agendas and materials, documenting decisions, and helping track action items across multiple teams and institutions.
Another major deliverable is the program's shared web presence and information infrastructure. The Coordinating Center must create and maintain CEECR websites, which generally serve both internal needs (secure collaboration spaces, documentation repositories, announcements, calendars) and external needs (public-facing descriptions of the program, resources, policies, and potentially summaries of available data or procedures). Just as important, the Center is tasked with facilitating deposition of data into NIH repositories. That implies practical support to help cohorts prepare data and associated documentation for submission, ensure compliance with NIH data sharing expectations, and encourage use of consistent metadata and formats that make deposited datasets discoverable and reusable over time. By focusing on these connective tasks, the Coordinating Center helps ensure that the investment in multiple new cohorts yields a coherent, interoperable resource for the research community.
In terms of administrative details, this is a discretionary funding opportunity using a cooperative agreement mechanism, meaning NIH is expected to have substantial scientific or programmatic involvement compared with a standard grant. The estimated maximum annual budget is capped at $500,000 (award ceiling), and the opportunity anticipated making one award, indicating a single Coordinating Center would be selected to serve the entire CEECR network. The FOA was created on October 14, 2020, with an original application closing date of January 29, 2021. The program is listed under CFDA numbers 93.113, 93.393, and 93.399, reflecting its alignment with NIH and NCI/NIEHS research support portfolios.
Eligibility is broad and includes many types of organizations that could credibly run a national coordinating function. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as clarified in the FOA's additional eligibility information. This wide eligibility reflects the operational nature of the work, where success depends on demonstrated capacity to manage complex multi-site coordination, data standardization, communications infrastructure, and repository submissions rather than on being any one specific type of institution.
Overall, this opportunity is essentially funding the backbone of the CEECR initiative: a central team responsible for aligning procedures, supporting collaboration, maintaining shared program infrastructure, and ensuring that the cohorts generate harmonized data and biospecimens that can be deposited, shared, and analyzed in ways that advance understanding of how environmental exposures influence cancer risk across diverse populations.Apply for RFA CA 20 050
- The Department of Health and Human Services, National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "New Cohorts for Environmental Exposures and Cancer Risk (CEECR) Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.393, 93.399.
- This funding opportunity was created on Oct 14, 2020.
- Applicants must submit their applications by Jan 29, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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